PhD candidate in biophysics or engineering • Forschungszentrum caesar • Bonn

Discussion in 'Học bổng PhD' started by Chien Hoang, Oct 6, 2016.

  1. Chien Hoang

    Chien Hoang Administrator Staff Member

    Open Positions 1
    Time Span 02 Jan 2017 for 3 years
    Application Deadline 30 Nov 2016
    Financing yes
    Type of Position
    • PhD - Individual Supervisor
    Field of Research
    • Mathematics / Natural Sciences
    Subjects Biophysic / Engineering
    Description The center of advanced european studies and research (caesar) in Bonn, Germany, is an Institute of the Max Planck Society dedicated to the Neurosciences, Cell Biology, and Biophysics. The Max Planck Research Group “Structural Dynamics of Proteins” of Dr. Elmar Behrmann is looking for

    Ph.D. candidate (m/f) - Reference: FF-PhD-Ch 2016
    (background in biophysics or engineering)
    starting 01.01.2017 (open until a suitable candidate is found)

    to join a concerted research effort to uncover the molecular mechanism of voltage-gating in ion channels by functional cryo-electron microscopy.

    Project description
    Your main task within the concerted effort will be to develop the technical instrumentation required to unveil the molecular mechanism of voltage-dependent gating. With regard to ion channels, electron microscopy is currently lacking a strategy to prepare samples at defined membrane potentials. Using advanced nanofabrication techniques, especially focused ion beam milling in combination with scanning electron microscopy, you will design and optimize a technical solution to overcome this limitation. Designs will be tested and validated using correlative light- and electron-microscopy strategies, as well as by molecular cryo-electron microscopy of voltage-sensitive proteins prepared within this concerted research effort.

    What do we offer
    We offer a fixed-term contract for 3 years including social benefits, with the possibility of limited extension if required to conclude the project. You will work in a young and dynamic environment, embedded in the scientific community of the Max Planck Society and the universities of Bonn and Cologne. Caesar is part of a cluster for neuroscience in the Bonn-Cologne region, comprising the German Center for Neurodegenerative Diseases and two Max Planck Institutes. The Institute hosts the International Max Planck Research School for Brain & Behavior and is involved in the Bonn International Graduate School of Neuroscience.

    Caesar seeks to increase the number of female scientists and encourages them to apply. Handicapped persons with comparable qualifications receive preferential status.
    Requirements Who are we looking for
    Candidates must have a M.Sc. degree in a relevant field. Successful candidates will have proven experience adapting sophisticated instrumentation to their needs, or a background in engineering and a strong interest in biophysics. Prior experience in fluorescence microscopy, optimally using voltage-sensitive reporters, is a strong benefit. Prior exposure to physics modeling software tools, such as COMSOL or open-source alternatives, is also a benefit. Similarly, prior exposure to the subject of structural biology, whether from an experimentalists or a theoretical/modeling point of view, is a plus.
    We are looking for a candidate with a keen interest in contributing to the understanding of the structural mechanisms in neurobiology. Candidates should be self-motivated, able and willing to learn new techniques, and not afraid of working with computers and high-end FIB/SEMs.
    Working Language
    • English
    Language of Dissertation
    • English
    Required Documents
    • CV
    • Reports, certificates
    • Transcripts
    • Letter of Motivation
    More Information

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